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Dihexa

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Dihexa is a synthetic oligopeptide used in neuroscience research to examine HGF/c-Met signaling, synaptogenesis, and cognitive-function pathways. Developed as a potent angiotensin IV analog, Dihexa is studied for its reported ability to facilitate HGF dimerization and neurotrophic signaling in preclinical memory and neurodegeneration models.

  • Research class: HGF/c-Met pathway activating peptide analog
  • Primary research purpose: Investigation of hepatocyte growth factor signaling, synaptic plasticity, and neurotrophic support markers
  • Research focus: c-Met receptor activation, dendritic spine density readouts, and cognitive-behavior model endpoints
  • Common research endpoints: HGF pathway markers, synaptophysin/PSD-95 expression, Morris water maze parameters, and neurite outgrowth assays

For research use only. Not for therapeutic or diagnostic applications.

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Certificate of analysis

Batch
PL-2608-F
Purity
98.3%
Method
HPLC / MS
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All products are sold for laboratory research use only. Not for human or veterinary consumption, diagnostic or therapeutic use.

Description

Dihexa

  • Chemical name: N-hexanoic-Tyr-Ile-(6) aminohexanoic amide (commonly cited structure)
  • Structure type: Synthetic hexapeptide / angiotensin IV-derived analog
  • Molecular weight: ~839 g/mol (verify against COA)
  • Synonyms: PNB-0408, HGF dimerization facilitator peptide
  • Research class: c-Met/HGF pathway neurotrophic peptide analog
  • Typical appearance: White to off-white powder
  • Storage notes: Store per COA; protect from moisture and light

Research background: Dihexa emerged from angiotensin IV analog research and has been studied preclinically for potent HGF/c-Met activation linked to synaptic repair and cognitive performance readouts.

Additional information

Size

10mg

Shipping

Orders are dispatched domestically within the USA through major carriers, with tracking issued at dispatch. Orders placed before the daily cut-off usually leave the same business day; anything after it goes out the next.

Storage

Lyophilised material is stable at room temperature in transit. On arrival, store refrigerated at 2–8°C and protected from light. Once reconstituted, keep refrigerated and use within the window appropriate to the compound.

Documentation

The certificate of analysis for your batch is filed against the batch number printed on the vial and stays available after purchase.

All products are sold for laboratory research use only. Not for human or veterinary consumption, diagnostic or therapeutic use.

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